Selecting a reliable BZP supplier is a critical decision for forensic laboratories, research institutions, and analytical chemistry facilities across Europe. CityChems provides high-quality benzylpiperazine (BZP) reference standards to the European research community, combining rigorous quality specifications with professional service and competitive pricing.
Benzylpiperazine—commonly known as BZP—is a synthetic piperazine derivative classified as a certified reference material (CRM) for research and forensic applications . First synthesized in the 1940s, BZP has become a compound of significant interest in forensic toxicology, neuropharmacology, and analytical chemistry . Despite its long history, the pharmacokinetic profile of BZP remains surprisingly underexplored, with only a few experimental studies investigating its behaviour in the human body .
Why Choose CityChems as Your BZP Supplier?
When evaluating a benzylpiperazine vendor, several factors distinguish a professional supplier from less reliable sources. CityChems offers the following advantages for European research institutions.
- High Purity Standards: Our BZP powder meets ≥98% purity specifications, enabling precise LC-MS and GC-MS calibration curves for defensible quantitative data in forensic toxicology . Certified reference materials with verified purity are essential for analytical method development and quality control .
- European Distribution: Our supply chain is optimised for UK and European customers, offering straightforward logistics and delivery.
- Professional Service: Our support team is available to assist with product inquiries and order processing.
- Secure Platform: We provide a protected online environment for all transactions.
- Transparent Communication: We provide clear, factual information about our products and services.
Product Specifications
- Name: 1-Benzylpiperazine (BZP)
- Synonyms: N-Benzylpiperazine
- CAS Number: 5321-63-1
- Molecular Formula: C₁₁H₁₆N₂
- Molecular Weight: 176.26 g/mol
- Appearance: White to off-white crystalline powder
- Purity: ≥98%
- Storage: Powder stable for 3 years at -20°C
- Solubility: 30 mg/mL in DMSO and DMF
- Classification: Analytical reference material; regulated as a Schedule I compound in some jurisdictions
Research and Forensic Applications
BZP is a valuable analytical reference standard for several domains:
- Forensic Toxicology: BZP is widely used as a certified reference standard for GC-MS and LC-MS testing methods in clinical toxicology and urine drug screening . Analytical reference materials with ≥98% purity enable precise calibration curves. BZP has stimulant properties and is regulated as a Schedule I compound in the United States .
- Pharmacokinetic Studies: Recent research has characterised BZP’s ADME profile using multi-platform in silico approaches. Studies indicate high oral bioavailability (96.7%), moderate volume of distribution (2.6 L/kg), and rapid clearance (10.81 mL/min/kg) . BZP is predicted to be primarily metabolised by CYP2D6 (up to 88% probability), with eight metabolites identified . In healthy humans following a 200 mg oral dose, BZP reached peak plasma concentration of approximately 262 ng/mL within 75 minutes, with an elimination half-life of approximately 5.5 hours .
- Method Development: BZP is used in developing and validating analytical methods for detecting piperazine derivatives. Substituting 2-BZP with structurally similar piperazines, such as 1-BZP or TFMPP, is not scientifically valid due to fundamental differences in molecular geometry, physicochemical properties, and intended analytical application .
- Neuropharmacology: Researchers study BZP to understand monoamine transporter systems. BZP acts as a monoamine transporter ligand with a particular affinity for stimulating dopamine release.
Why Customers Choose CityChems
- Reliable Quality: We source our products from reputable manufacturers and ensure they meet specifications required for professional research.
- European Logistics: Our supply chain is optimised for European customers, offering straightforward shipping and delivery.
- Expert Support: Our team understands the needs of researchers and can assist with product inquiries.
- Secure Ordering: Your privacy and security are our priorities.
Frequently Asked Questions
1. What is BZP?
BZP, or 1-Benzylpiperazine, is a synthetic piperazine derivative classified as an analytical reference standard for forensic and research applications . It has stimulant properties and is regulated as a Schedule I compound in the United States .
2. What is the purity of your BZP powder?
We provide BZP powder with ≥98% purity, suitable for research and forensic applications . This level of purity enables precise LC-MS and GC-MS calibration curves.
3. What are the storage conditions for BZP?
For long-term stability, BZP powder should be stored at -20°C. The powder is stable for 3 years under these conditions .
4. What are the pharmacokinetic properties of BZP?
In silico studies indicate high oral bioavailability (96.7%), moderate volume of distribution (2.6 L/kg), and rapid clearance . In humans, peak plasma concentration occurs at 75 minutes, with a half-life of approximately 5.5 hours .
5. What are the applications of BZP in research?
BZP is used in forensic toxicology as an analytical reference standard, in neuropharmacology to study monoamine transporter systems, and in method development for detecting piperazine derivatives .
6. Is BZP soluble in common laboratory solvents?
BZP exhibits defined solubility: 30 mg/mL in DMSO and DMF . This makes it suitable for preparing stock solutions and calibrants.
7. Is BZP legal in Europe?
The legal status of BZP varies by jurisdiction. It is regulated as a Schedule I compound in the United States . It is the responsibility of each researcher to verify the regulations in their country. CityChems supplies BZP exclusively for research and forensic applications.
8. What is the BZP wholesale pricing?
BZP wholesale pricing varies depending on quantity and specific requirements. Contact our team or visit the product page for current pricing information.